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study osteoarthritis association control hip oa university knee oa phenotype finition hand oa rotterdam research result cohort analysis effect finite allele osteophyte rheum table grade rotterdam study arthritis radiographic genome-wide subject esr 2 gene women meta-analysi consortium population polymorphism genetic score kerkhof osteoporotic fractures netherland heterogeneity department oa phenotypes gdf 5 rs 7775 center analyses meulenbelt knee osteoarthritis cartilage k /l score summary replication fracture finite osteophyte valde genome-wide association study criteria haplotype chingford study chingford model hospital genet health spector variant finite osteophytes caucasian disease joint meulenbelt i rs 288326 oxford hip roa figure gpr 22 rs 1256031 iceland estimate standardization progression
5 Most Recent Publications
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Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study
(Article)
Panoutsopoulou, K. Southam, L. Deloukas, P. Doherty, M. McCaskie, A. Ollier, W.E.R. Ralston, S.H. Spector, T.D. Valdes, A.M. Wallis, G.A. Wilkinson, J.M. Battley, K. Elliott, K.S. Blackburn, H. Blanco, F.J. Bumpstead, S. Cupples, L.A. Day-Williams, A.G. Dixon, K. Esko, T. Evangelou, E. Felson, D. Gómez-Reino, J.J. Wrayner, N. Gonzalez, A. Gordon, A. Gwilliam, R. Halldorsson, B.V. Hauksson, V.B. Hofman, B. Hunt, S.E. Ioannidis, J.P.A. Ingvarsson, T. Jonsdottir, I. Zhai, G. Jonsson, H. Keen, R. Kerkhof, H.J.M. Kloppenburg, M. Koller, N. Lakenberg, N. Lane, N.E. Lee, A.T. Metspalu, A. Meulenbelt, I. Beazley, C. Nevitt, M.C. O'Neill, F. Parimi, N. Potter, S.C. Rego-Perez, I. Riancho, J.A. Sherburn, K. Slagboom, P.E. Stefansson, K. Styrkarsdottir, U. Thorleifsson, G. Sumillera, M. Swift, D. Thorsteinsdottir, U. Tsezou, A. Uitterlinden, A.G. Meurs, J.B.J. van Watkins, B. Wheeler, M. Mitchell, S. Zhu, Y. Arden, N.K. Zmuda, J.M. Zeggini, E. Loughlin, J. Carr, A.M. Chapman, K. |
2011-05-01
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Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: The TREAT-OA consortium
(Article)
Kerkhof, H.J.M. Meulenbelt, I. Doherty, S.A. Felson, D. Gonzalez, A. Gordon, A. Harilainen, A. Hart, D.J. Hauksson, V.B. Heliovaara, M. Hofman, A. Ikegawa, S. Akune, T. Ingvarsson, T. Jiang, Q. Jonsson, H. Jonsdottir, I. Kawaguchi, H. Kloppenburg, M. Kujala, U.M. Lane, N.E. Leino-Arjas, P. Lohmander, L.S. Arden, N.K. Luyten, F.P. Malizos, K.N. Nakajima, M. Nevitt, M.C. Pols, H.A.P. Rivadeneira Ramirez, F. Shi, D. Slagboom, E. Spector, T.D. Stefansson, K. Aromaa, A. Sudo, A. Tamm, A. Tamm, A.E. Tsezou, A. Uchida, A. Uitterlinden, A.G. Wilkinson, J.M. Yoshimura, N. Valdes, A.M. Meurs, J.B.J. van Bierma-Zeinstra, S.M.A. Carr, A.M. Cooper, C. Dai, J. Doherty, M. |
2011-03-01
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Common genetic variation in the Estrogen Receptor Beta (ESR2) gene and osteoarthritis: Results of a meta-analysis
(Article)
Kerkhof, H.J.M. Meulenbelt, I. Pols, H.A.P. Rivadeneira Ramirez, F. Slagboom, E. Spector, T.D. Stolk, L. Tsezou, A. Uitterlinden, A.G. Valdes, A.M. Meurs, J.B.J. van Carr, A.M. Gonzalez, A. Hart, D.J. Hofman, A. Kloppenburg, M. Lane, N.E. Loughlin, J. Nevitt, M.C. |
2010-11-16
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A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22
(Article)
Kerkhof, H.J.M. Lories, R.J. Thorleifsson, G. Zhai, G. Zhang, F. Zhu, Y. Breggen, R. van der Carr, A.M. Doherty, M. Felson, D. Gonzalez, A. Halldorsson, B.V. Meulenbelt, I. Hart, D.J. Hauksson, V.B. Hofman, A. Ioannidis, J.P.A. Kloppenburg, M. Lane, N.E. Loughlin, J. Luyten, F.P. Nevitt, M.C. Parimi, N. Jonsdottir, I. Pols, H.A.P. Rivadeneira Ramirez, F. Slagboom, E. Styrkarsdottir, U. Tsezou, A. Putte, T. van de Zmuda, J. Spector, T.D. Zwart, J-A. Uitterlinden, A.G. Valdes, A.M. Meurs, J.B.J. van Arp, P.P. Ingvarsson, T. Jhamai, M. Jonsson, H. Stolk, L. |
2010-02-01
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Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand
(Article)
Evangelou, E. Chapman, K. Hauksson, V.B. Hofman, A. Hart, D.J. Ikegawa, S. Ingvarsson, T. Jiang, Q. Jonsdottir, I. Jonsson, H. Kerkhof, H.J.M. Kloppenburg, M. Meulenbelt, I. Lane, N.E. Li, J. Lories, R.J. Meurs, J.B.J. van Näkki, A. Nevitt, M.C. Rodriguez-Lopez, J. Shi, D. Slagboom, P.E. Zwart, J-A. Karassa, F.B. Tsezou, A. Wallis, G.A. Watson, C.M. Spector, T.D. Uitterlinden, A.G. Valdes, A.M. Ioannidis, J.P.A. Loughlin, J. Carr, A.M. Doherty, M. Gómez-Reino, J.J. Gonzalez, A. Halldorsson, B.V. |
2009-06-01
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