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study osteoarthritis association control university sample variant research effect genome-wide replication knee oa allele rheum department expression cohort analysis trust signi table patient arcogen signal disease genetic ptgs 2 medicine ratio hospital arthritis wellcome frequency rotterdam value meta-analysi result radiographic american journal centre allelic institute oxford arthritis rheum article genotyping cartilage rs 4140564 rotterdam study genomic factor knee osteoarthritis figure netherland health european ficant allelic expression population epidemiology iceland tartu locus american school polymorphism gwa studies susceptibility wellcome trust consortium chromosome allele frequency valde imputation p value chondrocyte spector center region genome-wide association scan
4 Most Recent Publications
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A variant in MCF2L is associated with osteoarthritis
(Article)
Day-Williams, A.G. Southam, L. Keis, A. Kerkhof, H.J.M. Thorleifsson, G. Arden, N.K. Carr, A. Chapman, K. Deloukas, P. Loughlin, J. McCaskie, A. Ollier, W.E.R. Panoutsopoulou, K. Ralston, S.H. Spector, T.D. Wallis, G.A. Wilkinson, J.M. Aslam, N. Birell, F. Carluke, I. Joseph, J. Rai, A. Reed, M. Rayner, N.W. Walker, K. Doherty, S.A. Jonsdottir, I. Maciewicz, R.A. Muir, K.R. Metspalu, A. Rivadeneira Ramirez, F. Stefansson, K. Styrkarsdottir, U. Uitterlinden, A.G. Esko, T. Meurs, J.B.J. van Zhang, W. Valdes, A.M. Zeggini, E. Estrada Gil, J.K. Helgadottir, H.T. Hofman, A. Ingvarsson, T. Jonsson, H. |
2011-09-09
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Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study
(Article)
Panoutsopoulou, K. Southam, L. Deloukas, P. Doherty, M. McCaskie, A. Ollier, W.E.R. Ralston, S.H. Spector, T.D. Valdes, A.M. Wallis, G.A. Wilkinson, J.M. Battley, K. Elliott, K.S. Blackburn, H. Blanco, F.J. Bumpstead, S. Cupples, L.A. Day-Williams, A.G. Dixon, K. Esko, T. Evangelou, E. Felson, D. Gómez-Reino, J.J. Wrayner, N. Gonzalez, A. Gordon, A. Gwilliam, R. Halldorsson, B.V. Hauksson, V.B. Hofman, B. Hunt, S.E. Ioannidis, J.P.A. Ingvarsson, T. Jonsdottir, I. Zhai, G. Jonsson, H. Keen, R. Kerkhof, H.J.M. Kloppenburg, M. Koller, N. Lakenberg, N. Lane, N.E. Lee, A.T. Metspalu, A. Meulenbelt, I. Beazley, C. Nevitt, M.C. O'Neill, F. Parimi, N. Potter, S.C. Rego-Perez, I. Riancho, J.A. Sherburn, K. Slagboom, P.E. Stefansson, K. Styrkarsdottir, U. Thorleifsson, G. Sumillera, M. Swift, D. Thorsteinsdottir, U. Tsezou, A. Uitterlinden, A.G. Meurs, J.B.J. van Watkins, B. Wheeler, M. Mitchell, S. Zhu, Y. Arden, N.K. Zmuda, J.M. Zeggini, E. Loughlin, J. Carr, A.M. Chapman, K. |
2011-05-01
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Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22
(Article)
Evangelou, E. Valdes, A.M. Rayner, N.W. Southam, L. Zhai, G. Elliot, K.S. Hunt, S.E. Kerkhof, H.J.M. Styrkarsdottir, U. Zhu, Y. Meulenbelt, I. Lories, R.J. Karassa, F.B. Tylzanowski, P. Bos, S.D. |
2011-02-01
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Genome-wide Association Scan Identifies a Prostaglandin-Endoperoxide Synthase 2 Variant Involved in Risk of Knee Osteoarthritis
(Article)
Valdes, A.M. Loughlin, J. Abkevich, V. Ge, D. Hofman, A. Uitterlinden, A.G. Hart, D.J. Zhang, F. Zhai, G. Egli, R.J. Lanchbury, J. Spector, T.D. Timms, K.M. Meurs, J.J.B. van Southam, L. Wilson, S.G. Doherty, S. Lories, R.J. Luyten, F.P. Gutin, A. |
2008-06-06
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