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patient expression leukemia myeloid leukemia mutation survival myeloid cebpa sample blood study cytogenetic group 3-itd analysis vegfc flt 3-itd vegfr probe table factor figure evi 1 þ outcome kinase number prognostic adult cancer gene expression signi cohort level aml samples diagnosis 16ink protein probe sets wbc count flt 3-itd ratio result tumor count p 16ink expression erasmus mc aberration children growth value receptor relapse blood cell count oncology treatment evi 1 igsf 4 expression p 16ink ratio subtype difference ptk 787/zk 222584 gene expression profiles tumour mll-rearranged inhibitor validation signi ficantly fication 787/zk igsf 4 amsacrine event-free survival effect combination aml patients erasmu disease j clin oncol evi 1 overexpression event-free
10 Most Recent Publications
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Anaplastic lymphoma kinase aberrations in rhabdomyosarcoma: Clinical and prognostic implications
(Article)
Gaal, J.C. van Flucke, U.E. Roeffen, M.H.S. Bont, E.S.J.M. de Sleijfer, S. Mavinkurve-Groothuis, A.M.C. Suurmeijer, A.J.H. Graaf, W.T.A. van der Versleijen-Jonkers, Y.M.H. |
2012-01-20
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Prognostic impact of white blood cell count in intermediate risk acute myeloid leukemia: Relevance of mutated NPM1 and FLT3-ITD
(Article)
Jonge, H.J.M. de Valk, P.J.M. Bont, E.S.J.M. de Schuringa, J.J. Ossenkoppele, G.J. Vellenga, E. Huls, G. |
2011-09-01
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Vascular endothelial growth factor receptor 2 (VEGFR-2) signalling activity in paediatric pilocytic astrocytoma is restricted to tumour endothelial cells
(Article)
Sikkema, A.H. Bont, E.S.J.M. de Molema, G. Dimberg, A. Zwiers, P.J. Diks, S.H. Hoving, E.W. Kamps, W.A. Peppelenbosch, M.P. Dunnen, W.F.A. den |
2011-08-01
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Characterization of CEBPA mutations and promoter hypermethylation in pediatric acute myeloid leukemia
(Article)
Hollink, I.H.I.M. Heuvel-Eibrink, M.M. van den Trka, J. Baruchel, A. Creutzig, U. Pieters, R. Reinhardt, D. Zwaan, C.M. Arentsen-Peters, S.T.C.J.M. Zimmermann, M. Peeters, J. Valk, P.J.M. Balgobind, B.V. Sonneveld, E. Kaspers, G.J. Bont, E.S.J.M. de |
2011-03-01
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Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia
(Article)
Balgobind, B.V. Heuvel-Eibrink, M.M. van den Cayuela, J.M. Baruchel, A. Meyer, C. Marschalek, R. Trka, J. Stary, J. Beverloo, H.B. Pieters, R. Zwaan, C.M. Boer, M.L. den Menezes, R.X. de Reinhardt, D. Hollink, I.H.I.M. Arentsen-Peters, S.T.C.J.M. Wering, E.R. van Kaspers, G.J. Cloos, J. Bont, E.S.J.M. de |
2011-02-01
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High IGSF4 expression in pediatric M5 acute myeloid leukemia with t(9;11)(p22;q23)
(Article)
Kuipers, J.E. Coenen, E.A. Danen-van Oorschot, A.A. Boer, M.L. den Marschalek, R. Meyer, C. Pieters, R. Zwaan, C.M. Heuvel-Eibrink, M.M. van den Balgobind, B.V. Stary, J. Baruchel, A. Haas, V. de Bont, E.S.J.M. de Reinhardt, D. Kaspers, G.J. Cloos, J. |
2011-01-20
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High-frequency type I/II mutational shifts between diagnosis and relapse are associated with outcome in pediatric AML: Implications for personalized medicine
(Article)
Bachas, C. Schuurhuis, G.J. Haas, V. de Assaraf, Y.G. Kaspers, G.J. Cloos, J. Hollink, I.H.I.M. Kwidama, Z.J. Goemans, B.F. Zwaan, C.M. Heuvel-Eibrink, M.M. van den Bont, E.S.J.M. de Reinhardt, D. Creutzig, U. |
2010-10-14
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High VEGFC expression is associated with unique gene expression profiles and predicts adverse prognosis in pediatric and adult acute myeloid leukemia
(Article)
Jonge, H.J.M. de Valk, P.J.M. Kamps, W.A. Löwenberg, B. Bont, E.S.J.M. de Veeger, N.J.G.M. Elst, A. ter Boer, M.L. den Cloos, J. Haas, V. de Heuvel-Eibrink, M.M. van den Kaspers, G.J. Zwaan, C.M. |
2010-09-09
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EVI1 overexpression in distinct subtypes of pediatric acute myeloid leukemia
(Article)
Balgobind, B.V. Lugthart, S. Stary, J. Trka, J. Zimmermann, M. Beverloo, H.B. Pieters, R. Delwel, H.R. Zwaan, C.M. Heuvel-Eibrink, M.M. van den Hollink, I.H.I.M. Arentsen-Peters, S.T.C.J.M. Wering, E.R. van Graaf, S.S.N. de Reinhardt, D. Creutzig, U. Kaspers, G.J. Bont, E.S.J.M. de |
2010-05-01
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AML at older age: Age-related gene expression profiles reveal a paradoxical down-regulation of p16INK4A mRNA with prognostic significance
(Article)
Jonge, H.J.M. de Bont, E.S.J.M. de Huls, G. Valk, P.J.M. Schuringa, J.J. Kies, M. Woolthuis, C.M. Delwel, H.R. Veeger, N.J.G.M. Vellenga, E. Löwenberg, B. |
2009-11-19
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