Ernesto Godinho, M.F.

cancer breast bcar 4 resistance expression breast cancer tamoxifen receptor protein erbb 2 tamoxifen resistance estrogen breast cancer cells zr /bcar cells level cell lines patient pathway bcar 4 expression therapy tumor growth proliferation lapatinib antiestrogen factor zr -75-1 cells treatment chapter mechanism /bcar presence breast cancer res -75-1 study agthoven analysis estrogen receptor kinase survival j clin oncol antiestrogen resistance effect bcar 4-expressing cells cancer res inhibitor 4- oht medium zr /egfr cells phosphorylation activation esr 1 homologue culture control function erbb 3 erbb receptors development result clin cancer res breast cancer patients disease tissue breast cancers 2007. netherland gene expression model addition bcar 4 mrna inhibition estradiol tamoxifen treatment response 4- hydroxytamoxifen br j cancer nat rev cancer anti-estrogen progression