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protein expression mouse vector fibrosis 508del airway model brosi disease figure level fi brosis epithelial response activity study channel therapy macrophage physiol signi ficantly patient f 508del result secretion signi transduction conductance mutation infection analysis effect animal membrane regulator tissue control transmembrane flammatory treatment wild-type delivery function azithromycin transport kidney mucosa peptide virus cf mice glafenine table intestine cgk ii experiment ficantly phenotype pk 1 cells transfection transfer ifn -α / journal chloride liver activation cf patients ficiency solution 508-cftr cf lung disease condition mucus journal af /af mice epithelia difference sample f 508del mice integrin
10 Most Recent Publications
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Rescue of epithelial HCO 3 - secretion in murine intestine by apical membrane expression of the cystic fibrosis transmembrane conductance regulator mutant F508del
(Article)
Xiao, F. Li, J. Jonge, H.R. de Seidler, U. Singh, A.K. Riederer, B. Wang, J. Sultan, A. Park, H. Lee, M.G. Lamprecht, G. Scholte, B.J. |
2012-11-01
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Mouse models of cystic fibrosis: Phenotypic analysis and research applications
(Article)
Wilke, M. Buijs-Offerman, R.M. Aarbiou, J. Colledge, W.H. Sheppard, D.N. Touqui, L. Bot, A.G. Jorna, H. Jonge, H. de Scholte, B.J. |
2011-07-01
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Gene and cell therapy for cystic fibrosis: From bench to bedside
(Article)
Conese, M. Ascenzioni, F. Boyd, A.C. Coutelle, C. Fino, I. de Smedt, S. de Rejman, J. Rosenecker, J. Schindelhauer, D. Scholte, B.J. |
2011-07-01
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CFTR-deficiency renders mice highly susceptible to cutaneous symptoms during mite infestation
(Article)
Hashimoto, Y. Shuto, T. Shimasaki, S. Sugiyama, T. Scholte, B.J. Kai, H. Mizunoe, S. Tomita, A. Koga, T. Sato, T. Takeya, M. Suico, M.A. Niibori, A. Sugahara, T. |
2011-04-01
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Lentiviral gene therapy of murine hematopoietic stem cells ameliorates the Pompe disease phenotype
(Article)
Til, N.P. van Stok, M. Scholte, B.J. Lambrecht, B.N.M. Duncker, D.J.G.M. Ploeg, A.T. van der Reuser, A.J.J. Verstegen, M.M.A. Wagemaker, G. Aerts Kaya, F.S.F. Waard, M.C. de Farahbakhshian, E. Visser, T.P. Kroos, M.A. Jacobs, E.H. Willart, M.A. Wegen, P. van der |
2010-07-01
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Delivery of DNA and siRNA by novel gemini-like amphiphilic peptides
(Article)
Damen, M. Aarbiou, J. Dongen, S.F.M. van Buijs-Offerman, R.M. Spijkers, P.P. Heuvel, M. van den Kvashnina, K. Nolte, R.J.M. Scholte, B.J. Feiters, M.C. |
2010-07-01
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Correction of the ΔPhe508 cystic fibrosis transmembrane conductance regulator trafficking defect by the bioavailable compound glafenine
(Article)
Robert, R. Carlile, G.W. Scholte, B.J. Thomas, D.Y. Hanrahan, J.W. Liao, J. Balghi, H. Lesimple, P. Liu, L.-J. Kus, B. Rotin, D. Wilke, M. Jonge, H.R. de |
2010-06-01
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Azithromycin reduces exaggerated cytokine production by M1 alveolar macrophages in cystic fibrosis
(Article)
Meyer, M. Huaux, F. Gavilanes, X. Brûle, S. van den Lebecque, P. Lo Re, S. Lison, D. Scholte, B.J. Wallemacq, P. Leal, T. |
2009-11-26
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Proteomic analysis of naphthalene-induced airway epithelial injury and repair in a cystic fibrosis mouse model
(Article)
Carvalho-Oliveira, I.M. Charro, N. Penque, D. Scholte, B.J. Aarbiou, J. Buijs-Offerman, R.M. Wilke, M. Schettgen, T. Kraus, T. Titulaer, M.K. Burgers, P.C. Luider, T.M. |
2009-07-06
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Combined antiviral activity of interferon-α and RNA interference directed against hepatitis C without affecting vector delivery and gene silencing
(Article)
Pan, Q. Henry, S.D. Metselaar, H.J. Scholte, B.J. Kwekkeboom, J. Tilanus, H.W. Janssen, H.L.A. Laan, L.J.W. van der |
2009-07-01
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