Peiris, M.

virus macaque disease hong kong sar alveolar d.p.i lesion scv-inoculated macaques hong kong proteinaceous fluid scv-infected macaques aetiological agent nature alveolar damage virus isolation scv infection press sars patients sars virus evere health laboratory centre university pathology building information virus particles re-isolated isolation queen mary hospital polymerase chain reaction infection postulate criteria syncytia geophy coronaviru rt-pcr patient world health organization health biopsied lung tissue criteria — isolation 3015 ge rotterdam negative-contrast electron microscopy aetiology fluid inoculated alveoli group multinucleated cells alveolar lumina sars case fluid mechanics nature med chlamydia pneumoniae planets 166–176 sars-associated coronavirus 5. peiris 435 deaths laboratory evidence autopsy material shek kip 96 individuals macaques display host cells mantle convection groups 2–5. rt-pcr analysis coronavirus morphology 3 d.p.i virus excretion 4 d.p.i 16 d.p.i vero cells cambridge univ host species lung tissue histopathological examinations 4. ksiazek days post-inoculation china § immunofluorescence assay alveolar macrophages suppurative rhinitis