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study association control osteoarthritis knee oa hand oa university analysis hip oa effect rotterdam study variant meta-analysi allele phenotype gdf 5 rs 7775 polymorphism rotterdam population table result summary figure grade rheum genetic heterogeneity arthritis genome-wide analyses subject rs 288326 women research osteoporotic fractures gpr 22 iceland estimate genet radiographic factor protein haplotype model intron cohort locus snp rs 3815148 oa phenotypes replication chingford study sample evidence summary ors susceptibility meulenbelt netherland criteria ioannidi cartilage random-effect discovery study genome-wide association study expression definition kerkhof joint lorie centre imputation doherty signal arcogen /or hand oa frzb rs 7775 dio 2 gene gdf 5 gene center credibility
3 Most Recent Publications
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A variant in MCF2L is associated with osteoarthritis
(Article)
Day-Williams, A.G. Southam, L. Keis, A. Kerkhof, H.J.M. Thorleifsson, G. Arden, N.K. Carr, A. Chapman, K. Deloukas, P. Loughlin, J. McCaskie, A. Ollier, W.E.R. Panoutsopoulou, K. Ralston, S.H. Spector, T.D. Wallis, G.A. Wilkinson, J.M. Aslam, N. Birell, F. Carluke, I. Joseph, J. Rai, A. Reed, M. Rayner, N.W. Walker, K. Doherty, S.A. Jonsdottir, I. Maciewicz, R.A. Muir, K.R. Metspalu, A. Rivadeneira Ramirez, F. Stefansson, K. Styrkarsdottir, U. Uitterlinden, A.G. Esko, T. Meurs, J.B.J. van Zhang, W. Valdes, A.M. Zeggini, E. Estrada Gil, J.K. Helgadottir, H.T. Hofman, A. Ingvarsson, T. Jonsson, H. |
2011-09-09
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A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22
(Article)
Kerkhof, H.J.M. Lories, R.J. Thorleifsson, G. Zhai, G. Zhang, F. Zhu, Y. Breggen, R. van der Carr, A.M. Doherty, M. Felson, D. Gonzalez, A. Halldorsson, B.V. Meulenbelt, I. Hart, D.J. Hauksson, V.B. Hofman, A. Ioannidis, J.P.A. Kloppenburg, M. Lane, N.E. Loughlin, J. Luyten, F.P. Nevitt, M.C. Parimi, N. Jonsdottir, I. Pols, H.A.P. Rivadeneira Ramirez, F. Slagboom, E. Styrkarsdottir, U. Tsezou, A. Putte, T. van de Zmuda, J. Spector, T.D. Zwart, J-A. Uitterlinden, A.G. Valdes, A.M. Meurs, J.B.J. van Arp, P.P. Ingvarsson, T. Jhamai, M. Jonsson, H. Stolk, L. |
2010-02-01
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Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand
(Article)
Evangelou, E. Chapman, K. Hauksson, V.B. Hofman, A. Hart, D.J. Ikegawa, S. Ingvarsson, T. Jiang, Q. Jonsdottir, I. Jonsson, H. Kerkhof, H.J.M. Kloppenburg, M. Meulenbelt, I. Lane, N.E. Li, J. Lories, R.J. Meurs, J.B.J. van Näkki, A. Nevitt, M.C. Rodriguez-Lopez, J. Shi, D. Slagboom, P.E. Zwart, J-A. Karassa, F.B. Tsezou, A. Wallis, G.A. Watson, C.M. Spector, T.D. Uitterlinden, A.G. Valdes, A.M. Ioannidis, J.P.A. Loughlin, J. Carr, A.M. Doherty, M. Gómez-Reino, J.J. Gonzalez, A. Halldorsson, B.V. |
2009-06-01
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