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prostate mouse cancer expression psa-cre tumor epithelial month model tissue hematopoietic control adult chromosome marrow tumours development prostate cancer 14 months staining inactivation study antibody gland mutation epithelial cells analysis marker recombination prostate lobes hyperplasia ly -6a gfp prostate epithelial cells transgene ly -6a metastase apoptosi 5 months proliferation luminal epithelial cells promoter number fragment result bone marrow proliferation rate prostate cancer development pten ko mice pten +/à mice mouse model alteration tumor development pten inactivation john wiley hyperplasia /pin lesions region control mice adult bone marrow phospho-akt lesion weight genomic luminal pheochromocytoma suppressor protein figure hybridization van der korput ly -6a cassette activity thymu enrichment spleen lung metastases pathol prostate-specific section hematopoietic tissues allele
4 Most Recent Publications
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Conditional Pten knock-out mice: A model for metastatic phaeochromocytoma
(Article)
Korpershoek, E. Loonen, A.J.M. Krijger, R.R. de Corvers, S. Nederveen, F.H. van Jonkers, J. Ma, X. Made, A.Z. van der Korsten, H. Trapman, J. Dinjens, W.N.M. |
2009-03-01
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Targeted biallelic inactivation of Pten in the mouse prostate leads to prostate cancer accompanied by increased epithelial cell proliferation but not by reduced apoptosis.
(Article)
Ziel-van der Made, A.C. Autar, B. Ma, X. Trapman, J. Korput, H.A.G.M. van der Vermeij, M. Duijn, P.W. van Cleutjens, C.B.J.M. Krijger, R.R. de Krimpenfort, P. Berns, A. Kwast, Th.H. van der |
2005-07-01
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Ly-6A/E(Sca-1) Gene Regulatory Elements in Hematopoletic Stem Cells in Mouse
(Doctoral Thesis)
Ma, X. |
2003-09-17
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The Ly-6A (Sca-1) GFP transgene is expressed in all adult mouse hematopoietic stem cells
(Article)
Ma, X. Robin, C.I. Ottersbach, K. Dzierzak, E.A. |
2002-01-01
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