Verhoef, S.

cancer family brca 1 variant breast mutation study model genetic breast cancer brca 2 number netherland carrier university breast cancer risk research genetics service patient department syndrome control probability analysis centre page number hospital citation purposes cutoff point attitude center member table diagnosis genet sequence germline information population brcapro result service tumor chek 2 cutoff chek 2 gene signi ficantly modifier tumour .1100delc li-fraumeni li-fraumeni syndrome children individual risk family members group proband history point score purpose citation polymorphism brca 2. repair index sample figure association family members regression index patient nevanlinna h xrcc 1 classification relative antoniou grant netherlands cancer institute phenotype