Meer, C.A. van der

cancer distress women carrier result study breast family level unfavourable test result testing risk carriers partner mutation anxiety distress levels depression breast /ovarian cancer subject relative unfavourable mutation carrier problem feeling unfavourable test outcome consequence test result pre-test outcome experience brca 1 prophylactic mastectomy children disease prophylactic regression model score scale variable period mastectomy interview /ovarian impact presymptomatic genetic 1/brca rotterdam future article 40 years woman thought regression sample increase participant december population breast cancer hospital presymptomatic testing nature questionnaire prophylactic surgery number factor model response blood surveillance tibben jmg.bmj.com downloaded implication presymptomatic dna testing counselling /blood sampling e j meijers-heijboer personality mutation carriers