Vliet, A. van

message strategy transmission ceftazidime concentration patient mail queue serum allatonce strategy msps strategy exudate deadline transmission cost queue message size cycle problem / european journal pharmacokinetic allatonce system arrival clearance edi system cycle g example antimicrobial journal study infusion chemotherapy ® rst body clearance pathogen antimicrobial agents result therapy regimen infection point heuristic theorem ratio creatinine clearance dosage 32 mg /l 4 mic research arrival time creatinine policy case ratio european sample dosing number archibald 380±391 group 8 mg /l capacity 1.5 g tds time t dosing interval agent interarrival time administration /24 proof fluid arrival times minimising partition 0.6 process interval minimise ® xed size aucexudate /aucserum ratio polynomial time heuristic