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repair protein rad 54 recombination replication figure damage rad 51 dna damage activity strand hyperthermia atpase rnf 20 dna repair level antibody atpase activity slx 4 number uv-light experiment pathway polymerase brca 2 rad 54 foci lesion response sirna result irradiation treatment mouse break molecule wild-type dna replication accumulation histone chromatin es cells rad 54 protein chapter mechanism error bars replication forks cancer -/- focus 17- dmag kanaar effect increase 37° c formation dsb repair control radiation double-strand uv irradiation rad 54k structure temperature efficiency absence synthesis error 41 ° c mol cell uv-induced dna damage hela cells slx 1 process inhibitor function nature 37 ° c 17- chromosomal presence
7 Most Recent Publications
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The response of mammalian cells to UV-light reveals Rad54-dependent and independent pathways of homologous recombination
(Article)
Eppink, B. Tafel, A.A. Hanada, K. Drunen, E. van Hickson, I.D. Essers, J. Kanaar, R. |
2011-11-10
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Mild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition
(Article)
Krawczyk, P.M. Eppink, B. Soullié, T. Rens, J.A.P. Verhagen, H.J.M. O'Connor, M.J. Frankene, N.A.P. Hagen, T.L.M. ten Kanaar, R. Aten, J.A. Essers, J. Stap, J. Rodermond, H. Odijk, H. Zelensky, A. Bree, C. van Stalpers, L.J. Buist, M.R. |
2011-06-14
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Requirement of ATM-Dependent Monoubiquitylation of Histone H2B for Timely Repair of DNA Double-Strand Breaks
(Article)
Moyal, L. Lerenthal, Y. Shkedy, D. Smorodinsky, N. Vliet, N. van Kuster, B. Mann, M. Ciechanover, A. Dahm-Daphi, J. Kanaar, R. Hu, M.-T. Chen, D.J. Gana-Weisz, M. Oren, M. Shiloh, Y. Mass, G. So, S. Wang, S-Y. Eppink, B. Chung, Y. Shalev, G. Shema, E. |
2011-04-08
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ATP-dependent and independent functions of Rad54 in genome maintenance
(Article)
Agarwal, S. Cappellen, W.A. van Guénolé, A. Eppink, B. Linsen, S.E.V. Meijering, E. Houtsmuller, A. Kanaar, R. Essers, J. |
2011-03-07
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Requirement of ATM-Dependent Monoubiquitylation of Histone H2B for Timely Repair of DNA Double-Strand Breaks
(Article)
Moyal, L. Lerenthal, Y. Shkedy, D. Smorodinsky, N. Vliet, N. van Kuster, B. Mann, M. Ciechanover, A. Dahm-Daphi, J. Kanaar, R. Hu, M.-T. Chen, D.J. Gana-Weisz, M. Oren, M. Shiloh, Y. Mass, G. So, S. Wang, S-Y. Eppink, B. Chung, Y. Shalev, G. Shema, E. |
2011-03-04
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The cellular process of homologous recombination and its applications in cancer biology
(Doctoral Thesis)
Eppink, B. |
2010-06-11
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Coordination of Structure-Specific Nucleases by Human SLX4/BTBD12 Is Required for DNA Repair
(Article)
Muñoz, I.M. Hain, K. Kanaar, R. Ponting, C.P. Lilley, D.M.J. Rouse, J. Déclais, A.C. Gardiner, M. Toh, G.W. Sanchez-Pulido, L. Heuckmann, J.M. Toth, R. Macartney, T. Eppink, B. |
2009-07-10
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