Haugarvoll, K.

disease parkinson 1441c carrier mutation parkinsonism substitution neurology 1441h family patient lrrk 2 haplotype study parkinson disease department kinase lrrk 2 gene lrrk 2 mutations mutation carriers university www.neurology.org research domain disorder feature protein analysis lrrk 2 protein ϯ sd age pathology figure symptom table r 1441h carriers cause medicine parkinson disease k founder variant onset information .4321c r 1441c part 2 r 1441h incidence evidence control population guest phase institute article downloaded genet kachergu penetrance dopaminergic cell loss range asymmetry van doeselaar m p.r 1441c mutation disord r 1441g age 50 years kinase 2 10.1212/01. wnl .0000304044.22253.03 frequency 20 families 1441g center genetic gtpase hospital estimate activity residue leucine-rich taiwan