Sampaio, C.

mutation disease parkinson patient lrrk 2 mutations study frequency family g 2019s mutation g 2019s control parkinsonism population 1441h lrrk 2 gene parkinson disease neurol sample neurology disord cause disorder pd cases variant identi gigyf portugal university orthostatic tremor parkin carrier table analysis department italy pd patients genet proband r 1441h lrrk 2 onset cohort tremor identi fied identi fication european portuguese country hospital haplotype di fonzo paper orthostatic fonzo lrrk 2-g mutation penetrance lrrk 2 mutation r 1441h mutation correia guedes prevalence / parkinsonism spain family history neurosci research autosomal criteria movement background behaviour disorder protein fication speci van doeselaar m gigyf 2 mutations complaint 1441g disease patients african participant