Berning, M. http://repub.eur.nl/res/aut/3098/ List of Publications en http://repub.eur.nl/static-eur/img/logo.png RePub, Erasmus University Rotterdam http://repub.eur.nl Effects of 16S rRNA gene mutations on tetracycline resistance in Helicobacter pylori (Article) http://repub.eur.nl/res/pub/10211/ 2003-01-01T00:00:00Z The triple-base-pair 16S rDNA mutation AGA(926-928)-->TTC mediates high-level tetracycline resistance in Helicobacter pylori. In contrast, single- and double-base-pair mutations mediated only low-level tetracycline resistance and decreased growth rates in the presence of tetracycline, explaining the preference for the TTC mutation in tetracycline-resistant H. pylori isolates.