Lapedes, A.S.

virus clone epitope influenza variant donor peptide ctl clones np 418 426- tetramer cross-reactive npesv infection npdti stimulation subtype npdsi ec 50 value hla-b h 1n subtype h 3n subtype assay recognition target avidity t cell clones heterosubtypic variants value target cells ec 50 values influenza virus vaccine ctl response resvir response 426- cross-reactive ctl strain table cytotoxic release h 1n viruses /netherland influenza viruses npdpi substitution r 10f antigenic heterosubtypic cytotoxic t lymphocytes /victoria staining h 3n viruses titer netherland ctl clone npdsi tetramers specificity npesv tetramers position complex concentration 0.1 distance 2 mm glutamine rpmi 1640 medium lymphocytes virus-infected target cells h 1n virus h 3n virus npdti-specific cells npesv-specific virus-specific npdpi tetramers resvir -9 *3501-peptide epitope variants npesv-specific cells antigenic dissimilarity donor 1