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patient methylation glioblastoma cancer survival radiotherapy treatment tumor trial model temozolomide analysis study hrqol status prognostic promoter value glioma group factor baseline probe eortc oncol recurrence fication methylated classi outcome research score hrqol scores location dataset mgmt methylation bene fit sample classi fication methylation status university prediction mgmt promoter methylation mgmt-stp phase brain quality table pattern result mgmt methylation status -450k probability region mgmt-stp 27 van den grade mgmt promoter hm -450k unmethylated therapy expression month chemotherapy tumour prognostic factors 1.0 surgery prognostic value lesion 0.8 0.0 mgmt-stp 27 model 0.6 mgmt status 0.4 0.2 resection stupp island
4 Most Recent Publications
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MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status
(Article)
Bady, P. Sciuscio, D. Mcdonald, D.R. Lacombe, D. Stupp, R. Delorenzi, M. Hegi, M.E. Diserens, A.C. Bloch, J. Bent, M.J. van den Marosi, C. Dietrich, P-Y. Weller, M. Mariani, L. Heppner, F.L. |
2012-10-01
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Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
(Article)
Stupp, R. Hegi, M.E. Hau, P. Brandes, A. Gijtenbeek, J. Marosi, C. Vecht, C.J. Mokhtari, K. Wesseling, P. Villa, S. Eisenhauer, E. Gorlia, T. Mason, W.P. Weller, M. Lacombe, D. Cairncross, J.G. Mirimanoff, R.O. Bent, M.J. van den Taphoorn, M.J. Janzer, R.C. Ludwin, S.K. Allgeier, A. Fisher, B. Belanger, K. |
2009-05-01
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A novel tool to analyze MRI recurrence patterns in glioblastoma
(Article)
Wick, W. Stupp, R. Rorden, C. Karnath, H.O. Beule, A.C. Bromberg, J.E.C. Ernemann, U. Platten, M. Marosi, C. Mason, W.P. Bent, M.J. van den Weller, M. |
2008-12-01
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The prognostic value of health-related quality-of-life data in predicting survival in glioblastoma cancer patients: Results from an international randomised phase III EORTC Brain Tumour and Radiation Oncology Groups, and NCIC Clinical Trials Group study
(Article)
Mauer, M. Stupp, R. Mirimanoff, R.O. Forsyth, P. Bent, M.J. van den Weller, M. Bottomley, A. Taphoorn, M.J. Coens, C. Osoba, D. Marosi, C. Wong, R. Witte, O. de Cairncross, J.G. Efficace, F. |
2007-07-31
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