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scopus: 21834407100

Hollink, I.H.I.M.

(Iris Hollink)


mutation patient leukemia myeloid leukemia myeloid expression aberration cebpa study npm 1 mutations 3/itd adult group blood sample analysis prognostic flt 3/itd wt 1 mutations childhood event outcome cn-aml cytogenetic 98/nsd children table figure survival probe frequency cohort difference prognostic impact nup 98/nsd result wild-type oncology 1-mutated treatment relapse cancer impact factor number childhood aml subtype diagnosis type-ii mll-ptd type-ii aberrations type-i value adult aml wt 1 expression nup 98/nsd cases chapter mll –ptd wt 1 gene cebpa mutations tandem duplication flt 3 signi npm 1 duplication evi 1 þ aml cases subgroup zwaan cm zimmermann m wt 1 mutation tandem karyotype protocol characteristic aml patients fusion profile idh 1 cytogenetically




10 Most Recent Publications

Molecular Genetic Insights in Cytogenetically-Normal Pediatric Acute Myeloid Leukemia (Doctoral Thesis)
Hollink, I.H.I.M.
2011-11-16
Prevalence and prognostic value of IDH1 and IDH2 mutations in childhood AML: A study of the AML-BFM and DCOG study groups (Article)
Damm, F. Thol, F. Krauter, J. Heuser, M. Ganser, A. Thiede, C. Hollink, I.H.I.M. Zimmermann, M. Reinhardt, K. Heuvel-Eibrink, M.M. van den Zwaan, C.M. Haas, V. de Creutzig, U. Klusmann, J.-H.
2011-11-01
Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia (Article)
Balgobind, B.V. Hollink, I.H.I.M. Zemanová, Z. Stary, J. Cayuela, J.M. Baruchel, A. Creutzig, U. Reinhardt, D. Pieters, R. Michel Zwaan, C. Heuvel-Eibrink, M.M. van den Arentsen-Peters, S.T.C.J.M. Zimmermann, M. Harbott, J. Beverloo, H.B. Bergh, A.R.M. von Cloos, J. Kaspers, G.J. Haas, V. de
2011-10-01
NUP98/NSD1 characterizes a novel poor prognostic group in acute myeloid leukemia with a distinct HOX gene expression pattern (Article)
Hollink, I.H.I.M. Heuvel-Eibrink, M.M. van den Trka, J. Baruchel, A. Zimmermann, M. Creutzig, U. Reinhardt, D. Pieters, R. Valk, P.J.M. Zwaan, C.M. Arentsen-Peters, S.T.C.J.M. Pratcorona, M. Abbas, S. Kuipers, J.E. Galen, J.F. Beverloo, H.B. Sonneveld, E. Kaspers, G.J.J.L.
2011-09-29
Characterization of CEBPA mutations and promoter hypermethylation in pediatric acute myeloid leukemia (Article)
Hollink, I.H.I.M. Heuvel-Eibrink, M.M. van den Trka, J. Baruchel, A. Creutzig, U. Pieters, R. Reinhardt, D. Zwaan, C.M. Arentsen-Peters, S.T.C.J.M. Zimmermann, M. Peeters, J. Valk, P.J.M. Balgobind, B.V. Sonneveld, E. Kaspers, G.J. Bont, E.S.J.M. de
2011-03-01
Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia (Article)
Balgobind, B.V. Heuvel-Eibrink, M.M. van den Cayuela, J.M. Baruchel, A. Meyer, C. Marschalek, R. Trka, J. Stary, J. Beverloo, H.B. Pieters, R. Zwaan, C.M. Boer, M.L. den Menezes, R.X. de Reinhardt, D. Hollink, I.H.I.M. Arentsen-Peters, S.T.C.J.M. Wering, E.R. van Kaspers, G.J. Cloos, J. Bont, E.S.J.M. de
2011-02-01
High-frequency type I/II mutational shifts between diagnosis and relapse are associated with outcome in pediatric AML: Implications for personalized medicine (Article)
Bachas, C. Schuurhuis, G.J. Haas, V. de Assaraf, Y.G. Kaspers, G.J. Cloos, J. Hollink, I.H.I.M. Kwidama, Z.J. Goemans, B.F. Zwaan, C.M. Heuvel-Eibrink, M.M. van den Bont, E.S.J.M. de Reinhardt, D. Creutzig, U.
2010-10-14
No prognostic impact of the WT1 gene single nucleotide polymorphism rs16754 in pediatric acute myeloid leukemia (Article)
Hollink, I.H.I.M. Heuvel-Eibrink, M.M. van den Creutzig, U. Pieters, R. Reinhardt, D. Zwaan, C.M. Zimmermann, M. Balgobind, B.V. Arentsen-Peters, S.T.C.J.M. Alders, M. Willasch, A.M. Kaspers, G.J. Trka, J. Baruchel, A.
2010-10-01
Low frequency of MLL-partial tandem duplications in paediatric acute myeloid leukaemia using MLPA as a novel DNA screenings technique (Article)
Balgobind, B.V. Hollink, I.H.I.M. Zwaan, C.M. Heuvel-Eibrink, M.M. van den Reinhardt, D. Wering, E.R. van Graaf, S.S.N. de Baruchel, A. Stary, J. Beverloo, H.B. Greef, G.E. de Pieters, R.
2010-07-01
EVI1 overexpression in distinct subtypes of pediatric acute myeloid leukemia (Article)
Balgobind, B.V. Lugthart, S. Stary, J. Trka, J. Zimmermann, M. Beverloo, H.B. Pieters, R. Delwel, H.R. Zwaan, C.M. Heuvel-Eibrink, M.M. van den Hollink, I.H.I.M. Arentsen-Peters, S.T.C.J.M. Wering, E.R. van Graaf, S.S.N. de Reinhardt, D. Creutzig, U. Kaspers, G.J. Bont, E.S.J.M. de
2010-05-01