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protein t-all leukemia sample analysis patient figure ptpn 2 level assay mutation fusion notch blood clonal ba /f cells immunobead lymphoblastic leukemia expression ce-ssca erasmus mc control detection bcr –abl result polyclonal inhibitor cancer activation value transcript genescan lymphoblastic pathway oncogenic jak 1 protease t-cell kinase antibody number jak 1 mutations lysate heteroduplex rearrangement method tyrosine cell lines sensitivity immunobead assay product heteroduplex analysis sequence myc protein levels deletion clonality jak 1 mutants experiment 4 1 c capillary electrophoresis genescan analysis cytometric myc expression adult signi mfi values patient samples cell lysates bcr –abl protein transcription erasmu m-bcr electrophoresis bd biosciences target myeloid pcr products notch 1 bcr –abl proteins 2012.
4 Most Recent Publications
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Capillary electrophoresis single-strand conformation analysis (CE-SSCA) for clonality detection in lymphoproliferative disorders
(Article)
Gonzalez, D. Rombout, P.D.M. Sarasquete, M.E. Villarese, P. Wren, D. Dongen, J.J.M. van Garcia-Sanz, R. Macintyre, E. Langerak, A.W. Groenen, P.J.T.A. |
2011-11-24
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PTPN2 negatively regulates oncogenic JAK1 in T-cell acute lymphoblastic leukemia
(Article)
Kleppe, M. Soulier, J. Tartaglia, M. Foa, R. Macintyre, E. Haferlach, T. Cools, J. Asnafi, V. Mentens, N. Hornakova, T. Knoops, L. Constantinescu, S. Sigaux, F. Meijerink, J.P.P. Vandenberghe, P. |
2011-06-30
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Posttranscriptional deregulation of MYC via PTEN constitutes a major alternative pathway of MYC activation in T-cell acute lymphoblastic leukemia
(Article)
Bonnet, M. Loosveld, M. Mamessier, E. Roulland, S. Morgado, E. Formisano-Tréziny, C. Dik, W.A. Langerak, A.W. Prebet, T. Vey, N. Michel, G. Gabert, J. Montpellier, B. Soulier, J. Macintyre, E. Asnafi, V. Payet-Bornet, D. Nadel, B. Navarro, J.-M. Quilichini, B. Picard, C. Cristofaro, J.D. Bagnis, C. Fossat, C. Hernandez, L. |
2011-06-16
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Flow cytometric immunobead assay for the detection of BCR-ABL fusion proteins in leukemia patients
(Article)
Weerkamp, F. Dekking, E. Poecke, N. van Lucio, P. Mendonça, A. Sedek, L. Szczepański, T. Kalina, T. Kovac, M. Hoogeveen, P.G. Flores-Montero Orfao, A. Ng, Y.Y. Macintyre, E. Lhermitte, L. Chen, R. Brouwer-De Cock, K.A.J. Linden, A. van der Noordijk, A.L. Comans-Bitter, W.M. Staal, F.J.T. Dongen, J.J.M. van Velden, V.H.J. van der Wai, H. Böttcher, S. Brüggemann, M. Sluijs, A.J. van der Koning, A. Boeckx, N. |
2009-04-24
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