Visser, M. de

patient mutation study anisotropy disease corticospinal tract bulbar-onset als diffusion tract limb-onset als control analysis tensor corticospinal motoneuron imaging signi ficantly neck pain table neurology motor nerve bulbar-onset matter sclerosis signi limb-onset diffusion tensor tractography root compression department value compression corpus callosum baseline netherland amyotrophic university diffusion tensor imaging p.a 467t mutation agreement phenotype anisotropy reduction voxel-based family brain genome-wide motoneuron disease phenotypes polg mutations ficantly group kappa voxel-based analysis study sample carrier radiculopathy involvement reduction result capsule voxel-based analysis institute cortex mitochondrial right tractography cohort variant anisotropy values motoneuron disease association onset replication illumina patient groups change callosum follow-up corpus feature downloaded