Avontuur, J.A.M.

l-name oxide nitric patient shock pressure sepsis effect infusion synthesis heart study nitric oxide inhibition level synthase blood l-name infusion nitric oxide synthesis plasma blood pressure inhibitor control oxygen resistance perfusion nitrite figure nitric oxide synthase concentration output chapter change increase production endotoxin-treated hearts reduction plasma levels endotoxin l-arginine value endotoxin-treated oxygen consumption response hypotension nitrate result baseline inducible release human endotoxemia administration cytokine animal autoregulation vasoconstriction artery factor 12 hours ischemia table constitutive control hearts model perfusion pressure consumption reactive hyperemia /nitrate mortality group tissue reactive vasodilatation hemodynamic enzyme ester palmer rm perfusion pressures methyl