Spuls, P.I.

patient psoriasis treatment study therapy guideline evidence dermatol ciclosporin effect dermatology efalizumab methotrexate table response disease infection plaque psoriasis grade author journal result combination factor infliximab european etanercept trial psoriasis vulgaris adalimumab efficacy reaction pasi 75 response level vulgari 12 weeks group plaque phototherapy compilation suppl quality increase arthritis safety jeadv liver side effects improvement dermatologist venereology academy 5–70 venereology guidelines pregnancy measure exposure pasi /bsa arthritis venereology pathirana symptom interaction acitretin malignancy reduction contraindication © 2009 retinoid randomized assessment serum placebo pasi 75 month recommendation 5 mg /kg alefacept erythema fumaric acid esters blood drug reactions