Welsing, P.

radiographic knee oa association cox -2 inhibitors event radiographic study inhibitor adipokine level subject tnsaid nsaid celecoxib event date cartilage osteoarthritis hospitalisation baseline control gi events cv events progression grade adiponectin leptin cv risk score disease rofecoxib diclofenac patient cohort presistin non-steroidal anti-inflammatory drugs plasma k &l grade resistin serum biomarker knee oa cox -2 inhibitor naproxen padiponectin metabolism rheum presence gender van spil pleptin cv risk table score gi risk anti-inflammatory arthritis regression marker ibuprofen non-steroidal regression coef ficients plasma adipokine levels incidence synovial variable check gastroprotective / osteoarthritis diabetes mellitus signi outcome population 1.00 signi ficant associations plasma adiponectin levels /or right knee netherland center early-stage knee oa trial biomarker levels gastroprotective agents