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level patient tumor igf-i study insulin effect concentration receptor hormone expression ghrelin culture glucose treatment somatostatin /liter release endocrinol subtype secretion octreotide igf-i bioactivity adenoma igfbp control adenomas administration som 230 portal sst 2 growth value prolactinoma metab endocrinology serum tissue bioactivity plasma library erasmus mc tumor cells saline table analog binding corticotroph sst expression gh levels sample ivgtt bromocriptine 7315 b cells inhibition group hormone release igf-i levels van koetsveld pm survivor baseline sst subtypes result prl release insulin sensitivity children hormone secretion corticotroph adenomas number medium sensitivity acylated 7315 b tumor 0.1 nonsurvivor ss-analog regulation portal vein therapy adenoma cells range
9 Most Recent Publications
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IGF-I bioactivity better reflects growth hormone deficiency than total IGF-I
(Article)
Varewijck, A.J. Lamberts, S.W.J. Uitterlinden, P. Hofland, L.J. Janssen, J.A.M.J.L. |
2011-07-01
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Effects of acute administration of acylated and unacylated ghrelin on glucose and insulin concentrations in morbidly obese subjects without overt diabetes
(Article)
Kiewiet-Kemper, R.M. Aken, M.O. van Lely, A.J. van der Weerd, K. van der Uitterlinden, P. Themmen, A.P.N. Hofland, L.J. Rijke, Y.B. de Delhanty, P.J.D. Ghigo, E. Abribat, T. |
2009-11-27
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Expression and functional analysis of dopamine receptor subtype 2 and somatostatin receptor subtypes in canine Cushing's disease
(Article)
Bruin, C. de Hanson, J.M. Meij, B.P. Kooistra, H.S. Waaijers, A.M. Uitterlinden, P. Lamberts, S.W.J. Hofland, L.J. |
2008-09-01
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Intravenous glucose administration in fasting rats has differential effects on acylated and unacylated ghrelin in the portal and systemic circulation: A comparison between portal and peripheral concentrations in anesthetized rats
(Article)
Gauna, C. Uitterlinden, P. Lely, A.J. van der Kramer, P. Kiewiet-Kemper, R.M. Janssen, J.A.M.J.L. Delhanty, P.J.D. Aken, M.O. van Ghigo, E. Hofland, L.J. Themmen, A.P.N. |
2007-11-01
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A single-dose comparison of the acute effects between the new somatostatin analog SOM230 and octreotide in acromegalic patients
(Article)
Hoek, J. van der Poon, K.W. Uitterlinden, P. Boerlin, V. Bruns, C. Lewis, I. Lamberts, S.W.J. Weckbecker, G. Hofland, L.J. Krahnke, T. Herder, W.W. de Feelders, R.A. Lely, A.J. van der |
2004-01-01
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Acute stress response in children with meningococcal sepsis: important differences in the growth hormone/insulin-like growth factor I axis between nonsurvivors and survivors
(Article)
Maingay-de Groof, F. Joosten, K.F.M. Kleijn, E.D. de Hazelzet, J.A. Hop, W.C.J. Uitterlinden, P. Doorn, J. van Hokken-Koelega, A.C.S. Janssen, J.A.M.J.L. |
2002-01-01
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Interferon-alpha-2a is a potent inhibitor of hormone secretion by cultured human pituitary adenomas
(Article)
Hofland, L.J. Herder, W.W. de Waaijers, M. Zuijderwijk, J. Uitterlinden, P. Koetsveld, P.M. van Lamberts, S.W.J. |
1999-01-01
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17-beta-estradiol-dependent regulation of somatostatin receptor subtype expression in the 7315b prolactin secreting rat pituitary tumor in vitro and in vivo
(Article)
Visser-Wisselaar, H.A. Uffelen, C.J. van Koetsveld, P.M. van Lichtenauer-Kaligis, E.G. Waaijers, A.M. Uitterlinden, P. Mooy, D.M. Lamberts, S.W.J. Hofland, L.J. |
1997-01-01
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Dissociation between the effects of somatostatin (SS) and octapeptide SS-analogs on hormone release in a small subgroup of pituitary- and islet cell tumors
(Article)
Hofland, L.J. Herder, W.W. de Visser-Wisselaar, H.A. Uffelen, C. van Waaijers, M. Zuyderwijk, J. Uitterlinden, P. Koetsveld, P.M. van Lamberts, S.W.J. Kros, J.M. |
1997-01-01
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