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som 230 somatostatin patient receptor effect level subtype sst 2 expression release adenomas adenoma secretion culture sst 5 receptors sst 5 study control gh release journal treatment corticotroph hormone /liter octreotide endocrinology analog arthritis adenoma cells endocrinol corticotroph adenomas sst 5 mrna adjuvant arthritis acromegalic patients metab concentration binding sst subtypes adjuvant inhibition lambert acth release basal acth release prl secretion -14 analogue 20 cells gh secretion acth secretion growth prolactinoma somatostatin receptor subtypes acromegalic somatostatin receptors van koetsveld pm prl release gh levels suppression srif -14 tissue disease 100 g oct tumor growth hormone sc injection affinity medium analysis culler md cushing glucose insulin sst 3 rat adjuvant arthritis acromegaly incubation value basal gh-secreting administration
4 Most Recent Publications
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The multi-ligand somatostatin analogue SOM230 inhibits ACTH secretion by cultured human corticotroph adenomas via somatostatin receptor type 5.
(Article)
Hofland, L.J. Hoek, J. van der Beckers, A. Lamberts, S.W.J. Feelders, R.A. Aken, M.O. van Koetsveld, P.M. van Waaijers, M. Sprij-Mooij, D. Bruns, C. Weckbecker, G. Herder, W.W. de |
2005-04-01
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A single-dose comparison of the acute effects between the new somatostatin analog SOM230 and octreotide in acromegalic patients
(Article)
Hoek, J. van der Poon, K.W. Uitterlinden, P. Boerlin, V. Bruns, C. Lewis, I. Lamberts, S.W.J. Weckbecker, G. Hofland, L.J. Krahnke, T. Herder, W.W. de Feelders, R.A. Lely, A.J. van der |
2004-01-01
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The novel somatostatin analog SOM230 is a potent inhibitor of hormone release by growth hormone- and prolactin-secreting pituitary adenomas in vitro
(Article)
Hofland, L.J. Lely, A.J. van der Weckbecker, G. Feelders, R.A. Lamberts, S.W.J. Beckers, A. Hoek, J. van der Koetsveld, P.M. van Herder, W.W. de Waaijers, M. Sprij-Mooij, D. Bruns, C. |
2004-01-01
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Somatostatin receptor subtype expression in cells of the rat immune system during adjuvant arthritis
(Article)
Bokum, A.M.C. ten Lichtenauer-Kaligis, E.G. Melief, M.J. Koetsveld, P.M. van Bruns, C. Hagen, P.M. van Hofland, L.J. Lamberts, S.W.J. Hazenberg, M.P. |
1999-01-01
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