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patient study polymorphism treatment response genotype month vkorc effect cyp 2c pharmacogenetic association hypertension therapy fi rst month sunitinib analysis clopidogrel disease factor variant warfarin allele heart blood platelet result arthritis vkorc 1 carrier erasmus universiteit rotterdam acenocoumarol netherland table rotterdam clin pharmacol pressure grade 3 hypertension receptor outcome statin survival aspirin signi number period heart failure resistance haplotype value cancer event university baseline fluence cyp 2c genotypes ef ficacy sunitinib treatment group pharmacol time-to-start mtx aspirin resistance level grade trial overanticoagulation vkorc 1 genotypes cycle enzyme population variation initiation methotrexate multivariate failure acenocoumarol users responder difference coumarin b-blocker
6 Most Recent Publications
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Polymorphisms in endothelial nitric oxide synthase (eNOS) and vascular endothelial growth factor (VEGF) predict sunitinib-induced hypertension
(Article)
Eechoute, K. Veldt, A.A.M. van der Mathijssen, R.H.J. Boven, E. Oosting, R.S. Kappers, M.H.W. Wessels, J.A.M. Gelderblom, H. Guchelaar, H.J. Reyners, A.K.L. Herpen, C.M.L. Haanen, J.B. |
2012-10-01
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Long-term anticoagulant effects of the CYP2C9 and VKORC1 genotypes in acenocoumarol users
(Article)
Verhoef, T.I. Orlewska, E. Visser, L.E. Maitland-van der Zee, A-H. Buikema, M.M. Schalekamp, T. Meer, F.J.M. van der Cessie, S. le Wessels, J.A.M. Schie, R.M.F. van Boer, A. de Teichert, M. |
2012-04-01
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A systematic review on pharmacogenetics in cardiovascular disease: Is it ready for clinical application?
(Article)
Verschuren, J.J.W. Trompet, S. Wessels, J.A.M. Guchelaar, H.J. Maat, M.P.M. de Simoons, M.L. Jukema, J.W. |
2012-01-01
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Myelosuppression by sunitinib is flt-3 genotype dependent
(Article)
Erp, N.P. van Mathijssen, R.H.J. Veldt, A.A.M. van der Haanen, J.B. Reyners, A.K.L. Eechoute, K. Boven, E. Wessels, J.A.M. Guchelaar, H.J. Gelderblom, H. |
2010-08-01
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Time to treatment as an important factor for the response to methotrexate in juvenile idiopathic arthritis
(Article)
Albers, H.M. Wessels, J.A.M. Huizinga, T.W.J. Cate, R. ten Guchelaar, H.J. Straaten, R.J.H.M. van der Brinkman, D.M.C. Suijlekom-Smit, L.W.A. Kamphuis, S.S.M. Girschick, H.J. Wouters, C. Schilham, M.W. Cessie, S. le |
2009-01-15
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Reply [3]
(Article)
Wessels, J.A.M. Huizinga, T.W.J. Guchelaar, H.J. Jonge, R. de |
2007-02-01
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