Höppener, J.W.M.

medullary thyroid carcinoma mutation thyroid 18ink calcitonin ret 2b mice cancer medullary patient plasma calcitonin levels carcinoma level plasma p 18ink tumor expression p 18ink expression mtc development oncogenic ret biomarker medullary thyroid cancer development imaging oncogenic protein receptor ret mutations mtc patients inhibitor month utrecht 12 months analysis cdk 4 table antibody study endocrinol cycle p 18ink proteins van veelen disease progression treatment result p 18ink mutants university cdk 6 suppressor ret proto-oncogene wildtype knockout kinase ret 2b prognostic mouse tissue netherland genotype veelen metastase group detection therapy genotype groups peptide department p 18 mutations p 18à/à mice 18 f-fdg uptake incidence tumorigenesi mtc incidence 9 months metab antigen medicine growth diagnosis gastrin