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18ink mutation ret 2b mice p 18ink plasma calcitonin levels p 18ink expression expression tumor cancer mtc development oncogenic ret calcitonin development level plasma oncogenic protein medullary thyroid carcinoma month 12 months analysis cdk 4 table thyroid cycle p 18ink proteins inhibitor utrecht p 18ink mutants cdk 6 suppressor carcinoma wildtype knockout ret 2b mouse netherland genotype genotype groups group department p 18 mutations p 18à/à mice incidence tumorigenesi medullary ret mutations mtc incidence 9 months result growth progression ink 4 proteins wildtype p 18ink transfected ret 2b mouse mutant research 18à/à effect 2os cells article 27kip koef fler hp p 18ink protein p 18 mutation p 18+/à mice interaction vector university 18+/à cancer research presence proliferation compound kinase family stability p 27+/à mice plasma calcitonin level
2 Most Recent Publications
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P18 is a tumor suppressor gene involved in human medullary thyroid carcinoma and pheochromocytoma development
(Article)
Veelen, W. van Klompmaker, R. Gloerich, M. Gasteren, C.J.R. van Kalkhoven, E. Berger, R. Lips, C.J.M. Medema, R.H. Höppener, J.W.M. Acton, D.S. |
2009-01-15
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Synergistic effect of oncogenic RET and loss of p18 on medullary thyroid carcinoma development
(Article)
Veelen, W. van Gasteren, C.J.R. van Acton, D.S. Franklin, D.S. Berger, R. Lips, C.J.M. Höppener, J.W.M. |
2008-03-01
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