Gruijl, F.R. de

repair cancer mouse wild-type ttd mice patient uv-induced defect keratinocyte animal exposure response xpc mice effect tumor damage csb / mice xeroderma xeroderma pigmentosum study ddb 2 syndrome csb / pigmentosum immunosuppression transcription genome nucleotide excision repair wild-type littermates protein littermate langerhan model csb mice sensitivity lesion transcription-coupled repair group dna damage uv exposure strain control genome repair fibroblast activity carcinogenesi mutation susceptibility level xpa mice hoeijmaker skin cancer fi broblasts trichothiodystrophy experiment synthesis netherland table wild-type mice radiation ficient predisposition ner-deficient van loveren garssen broblast genome ner excision uv-ddb uv dose expression uv-ddb activity csb-deficient csb-deficient mice figure difference contact hypersensitivity langerhans cell depletion dermatol uv irradiation