Zorn, C.N.

production cytokine triplicates ± sd il -6 pi 3k pathway il -1β production btk −/− bmmcs il -1β response activation result tnf -α pi 3k panel −/− immunol secretion effect lps-induced stimulation inhibitor proin flammatory cytokines wt bmmcs pathway point study triplicate receptor elisa btk-de ficient bmmcs germany ligand macrophage wortmannin flammatory btk +/+ p 110δ isoform protein concentration ficient proin huber ship 1−/− bmmcs lps-triggered costimulation experiment ficiency btk-de antigen kinase tlr-mediated bmmc cultures hochd örfer p 38 kinase 20 ng /ml supernatant calcium signalosome 20 min culture +/+ galano isoform 30 min calcium c-kit phosphorylation krystal combination p 110δ il -6 production lps-induced cytokine secretion h 2o production p 110δd bmmcs right panel tlr 2 tlr 4 l 138.8a mcs factor l 138.8a bmmcs amount