Burger-van Paassen, N.

muc 2‑/‑ mice expression 2‑/‑ paneth muc 2à/à mice butyrate muc 2 promoter protein effect coliti level infant colon preterm muc 2 synthesis mucin epithelial figure study synthesis promoter wt mice paneth cells muc 2 probiotic ls 174t cells disease patient bacteria analysis necrotizing enterocolitis response tissue concentration sample crypt development threonine goblet factor intestine increase function goblet cells preterm infants cytokine muc 2 expression epithelial cells enterocoliti defense pathway number growth antimicrobial result microbiota control activity table barrier necrotizing bowel mucus mucus layer difference layer change treatment muc 2‑/‑ activation reg 3β mechanism stimulation inflammation netherland length group model luminal van goudoever jb