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expression muc 2ϫ/ϫ mice muc 2à/à mice colon factor promoter cancer mucin muc 2/il mice muc 2 promoter muc 2 expression transcription wt mice epithelial muc 2 level muc 4 butyrate coliti study foxa 1 regulation protein binding activity goblet cells foxa 2 development goblet muc 5b mcc -555 effect response signi ficantly differentiation probe signi intestine muc 4 expression result analysis -555 ls 174t cells pathway experiment region figure gata -4 pparg number crypt activation tumor gata -6 mouse increase cytokine growth ficantly cmt -93 cells physiol journal flammatory receptor histone muc 5b promoter concentration 5 weeks seuningen vector tissue france ligand cdx -2 van seuningen proliferation control muc 2þ/þ mice pparg ligands murine
8 Most Recent Publications
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Colitis development during the suckling-weaning transition in mucin muc2-deficient mice
(Article)
Paassen, N.B.-V. Sluis, M. van der Bouma, J. Korteland-Van Male, A.M. Lu, P. Seuningen, I. van Boehm, G. Goudoever, J.B. van Renes, I.B. |
2011-10-01
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Colonic gene expression patterns of mucin muc2 knockout mice reveal various phases in colitis development
(Article)
Lu, P. Burger-van Paassen, N. Sluis, M. van der Witte-Bouma, J. Kerckaert, J.-P. Goudoever, J.B. van Seuningen, I. van Renes, I.B. |
2011-10-01
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The mouse Muc5b mucin gene is transcriptionally regulated by thyroid transcription factor-1 (TTF-1) and GATA-6 transcription factors
(Article)
Jonckheere, N. Velghe, A. Ducourouble, M.-P. Copin, M.-C. Renes, I.B. Seuningen, I. van |
2011-01-01
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The regulation of intestinal mucin MUC2 expression by short-chain fatty acids: Implications for epithelial protection
(Article)
Burger-van Paassen, N. Vincent, A. Puiman, P.J. Sluis, M. van der Bouma, J. Boehm, G. Goudoever, J.B. van Seuningen, I. van Renes, I.B. |
2009-06-01
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Peroxisome proliferator-activated receptor ligand MCC-555 suppresses intestinal polyps in ApcMin/+ mice via extracellular signal-regulated kinase and peroxisome proliferator-activated receptor-dependent pathways
(Article)
Yamaguchi, K. Cekanova, M. McEntee, M.F. Yoon, J.H. Fischer, S. Renes, I.B. Seuningen, I. van Baek, S.J. |
2008-10-22
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Combined defects in epithelial and immunoregulatory factors exacerbate the pathogenesis of inflammation: Mucin 2-interleukin 10-deficient mice
(Article)
Sluis, M. van der Bouma, J. Vincent, A. Velcich, A. Carraway, K.L. Büller, H.A. Einerhand, A.W.C. Goudoever, J.B. van Seuningen, I. van Renes, I.B. |
2008-06-24
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Forkhead box transcription factors Foxa1 and Foxa2 are important regulators of Muc2 mucin expression in intestinal epithelial cells
(Article)
Sluis, M. van der Vincent, A. Bouma, J. Male, A.K.V. Goudoever, J.B. van Renes, I.B. Seuningen, I. van |
2008-05-16
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The human mucin MUC4 is transcriptionally regulated by caudal-related homeobox, hepatocyte nuclear factors, forkhead Box A, and GATA endodermal transcription factors in epithelial cancer cells
(Article)
Jonckheere, N. Vincent, A. Seuningen, I. van Perrais, M. Ducourouble, M.-P. Male, A.K.V. Aubert, J.-P. Pigny, P. Carraway, K.L. Freund, J.-N. Renes, I.B. |
2007-08-03
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