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sox 2 protein pcl 2 import es cells chd 7 exp 4 target mouse development prc 2 control domain recruitment expression syndrome antibody binding prc 2 recruitment knockdown polycomb analysis histone target loci study 2-flag complex mutation chromatin interaction level factor pcl 2-flag cell biol embryo x inactivation function table pathway material gst-sox hmg box domain pcl 2-prc chromosome pcg target loci fraction experiment transcription shrna sox 2 peaks drosophila differentiation örlich x chromosome number charge syndrome inactivation importin regulation component extract 12.1 activity gst-sox 2 target genes imp - prc 2 complexes 2-prc nature imp 9 cargo genes dev charge pcg target genes mouse es cells imp - isoforms chd 7 peaks xx es cells x chromosome inactivation prc 2 occupancy
3 Most Recent Publications
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Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes
(Article)
Engelen, E. Akinci, U. Demmers, J.A. Rijkers, E.J. Bhattacharya, S. Philipsen, S. Pevny, L.H. Grosveld, F.G. Rottier, R. Lenhard, B. Poot, R.A. Bryne, J.C. Hou, J. Gontan, C. Moen, M.H. Szumska, D. Kockx, C. IJcken, W.F.J. van Dekkers, D.H. |
2011-06-01
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Polycomblike 2 facilitates the recruitment of PRC2 Polycomb group complexes to the inactive X chromosome and to target loci in embryonic stem cells
(Article)
Casanova, M. Preissner, T. Brockdorff, N. Cerase, A. Poot, R.A. Yamada, D. Li, X. Appanah, R. Bezstarosti, K. Demmers, J.A. Koseki, H. |
2011-04-01
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Exportin 4 mediates a novel nuclear import pathway for Sox family transcription factors
(Article)
Gontan, C. Guttler, T. Engelen, E. Demmers, J.A. Fornerod, M.W.J. Grosveld, F.G. Tibboel, D. Görlich, D. Poot, R.A. Rottier, R. |
2009-04-06
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