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scopus: 7004115322

Bouman, H.J.

(Heleen Bouman)


haplotype platelet clopidogrel p 2ry gene on-clopidogrel platelet reactivity patient study allele regimen reactivity dosing assay swets subs service effect aggregation study population verifynow haplotype allele on-clopidogrel figure result analysis response population snp rs 6787801 adp-induced variation variability dosing regimen c p 2ry locus clopidogrel dosing regimens association coll cardiol dosing regimens platelet reactivity reference j thromb haemost polymorphism aspirin rs 2046934 function artery disease intervention reference haplotype atherothrombotic events ht-snp difference percutaneou service receptor event cyp 2c haplotype f interindividual variability downloaded platelet function inhibition abcb 1 genes platelet function assays region p 2ry snps body mass index p 2ry haplotypes disease clopidogrel treatment haplotype effects smoking haplotype alleles platelet response cardiol loading dose sample size 6 minutes analyses genet thromb platelet aggregation loading diabetes sample




4 Most Recent Publications

Effect of gender difference on platelet reactivity (Article)
Breet, N.J. Sluman, M.A. Berkel, M.A.J.P.J. van Werkum, J.W. van Bouman, H.J. Harmsze, A.M. Kelder, J.C. Zijlstra, F. Hackeng, C.M. Berg, J.M. ten
2011-12-14
Is platelet inhibition due to thienopyridines increased in elderly patients, in patients with previous stroke and patients with low body weight as a possible explanation of an increased bleeding risk? (Article)
Breet, N.J. Donkersgoed, H.E. van Werkum, J.W. van Bouman, H.J. Kelder, J.C. Zijlstra, F. Hackeng, C.M. Berg, J.M. ten
2011-08-10
The influence of variation in the P2Y12 receptor gene on in vitro platelet inhibition with the direct P2Y12 antagonist cangrelor (Article)
Bouman, H.J. Werkum, J.W. van Rudež, G. Leebeek, F.W.G. Kruit, A. Hackeng, C.M. Berg, J.M. ten Maat, M.P.M. de Ruven, H.J.T.
2010-02-01
Common variation in the platelet receptor P2RY12 gene is associated with residual On-Clopidogrel platelet reactivity in patients undergoing elective percutaneous coronary interventions (Article)
Rudež, G. Bouman, H.J. Werkum, J.W. van Leebeek, F.W.G. Kruit, A. Ruven, H.J.T. Berg, J.M. ten Maat, M.P.M. de Hackeng, C.M.
2009-10-01