Remedios, C.D.

protein heart phosphorylation mybpc donor mybpc 3mut cmybp-c sarcomeric force heart failure failure cardiomyocyte function troponin figure sensitivity myocardium cardiomyopathy mutation 2ϩ sensitivity myosin dysfunction 2þ sensitivity myosin-binding protein c kinase troponin i expression hypertrophic cardiomyopathy patient signi ficantly sarcomeric function swets subs service level filament sarcomeric proteins hypertrophic erasmus university rotterdam tissue circulation isoform .2373dupg protein kinase muscle myosin-binding signi activity contractile phosphorylation status velden change group myocyte .2864_2865delct difference myo filament downloaded sarcomeric dysfunction boontje nm circ res study sarcomere chain sample force development effect carrier alteration development tombe pp zaremba r mybpc 3 mutations physiol antibody c .2373dupg foetal ctnt donor myocardium ficantly c .2864_2865delct mybpc 3 gene foetal