Horstmann, M.

t-all patient mutation leukemia lymphoblastic leukemia expression wt 1 mutations analysis mef 2c sample figure lymphoblastic score il 7r mutations study cluster pva score il -7r cancer identi fied coall t-all cases t-cell table 2-1 identi result rearrangement blood lmo 2 level il 7r nkx 2-1 deletion factor relapse group oncogene translocation tumor treatment childhood chromosomal survival number oncogenic il -7 therapy fication induction remission diagnosis notch 1 cells proliferative development profile resistance protein sensitivity wt 1 locus mef 2c expression alteration disease ba /f cells transcription outcome pathway inhibitor region t-all patients volume coall 06-97 study lmo 2 gene monoallelic notch 1 activation nature wild-type control