Richter-Unruh, A.

receptor mutation protein women leydig study netherland patient endocrinol expression hormone immigrant binding lhr protein group analysis non-western leydig cell hypoplasia leydig cell adenoma wt-lhr wild-type metab leydig cell hyperplasia non-western immigrants 578h mutation activity lhr gene luteinizing transfected result absence luteinizing hormone receptor addition library erasmus mc health cells transfected fraction signal surface hyperplasia lh receptor processing level morbidity membrane dutch factor signal transduction pathways adenoma transduction delivery wild-type lhr erasmus universiteit rotterdam erasmu localization difference pathway 44/42 caveolae cause university gonadotropin obstetric themmen ethnicity leydig cell adenomas phosphorylation induction sub-saharan african women cell surface n-linked region downloaded processing constitutively endosome tetracycline caveolin birth activation mother