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interaction receptor protein domain androgen activity expression binding t cells activation peptide mutation motif androgen receptor assay residue presence fxxlf n /c interaction tif 2 coactivator jurkat t cells experiment n-cor response transcriptional cho cells target ligand study ar lbd speci function ar fxxlf motif yeast jurkat surface tumor wild-type /well clonal cell lines level tetramer nh 2-terminal domain tissue lxxll antigen analysis transcription endocrinol cancer result reporter region wild-type ar clone pmhci structure r 1881 downloaded chain luciferase q 902k mutation surface expression wt tcr patient prostate pmhci /cd interaction control hormone 2-terminal medium variant target cells f 826l cell surface transactivation transfected transduced ar f 826l
10 Most Recent Publications
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T cell receptor fused to CD3ζ: Transmembrane domain of CD3ζ prevents TCR mis-pairing, whereas complete CD3ζ directs functional TCR expression
(Article)
Govers, C. Sebestyén, Z. Berrevoets, C.A. Venselaar, H. Debets, J.E.M.A. |
2011-10-11
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T cell activation upon exposure to patient-derived tumor tissue: A functional assay to select patients for adoptive T cell therapy
(Article)
Schroten-Loef, C. Kraaij, R. Veldhoven, J.L.M. Berrevoets, C.A. Bakker, M.A. den Sadelain, M. Bangma, C.H. Willemsen, R.A. Debets, J.E.M.A. |
2010-07-01
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MHC class I molecules with superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs
(Article)
Wooldridge, L. Clement, M. Debets, J.E.M.A. Berrevoets, C.A. Miles, J.J. Burrows, S.R. Price, D.A. Sewell, A.K. Lissina, A. Edwards, E.S.J. Ladell, K. Ekeruche, J. Hewitt, R.E. Laugel, B. Gostick, E. Cole, D.K. |
2010-04-01
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A novel mutation F826L in the human androgen receptor in partial androgen insensitivity syndrome; increased NH2-/COOH-terminal domain interaction and TIF2 co-activation
(Article)
Wong, H.Y. Hoogerbrugge, J.W. Wolffenbuttel, K.P. Trapman, J. Kleijer, W.J. Drop, S.L.S. Grootegoed, J.A. Brinkmann, A.O. Pang, K.L. Leeuwen, M. van Royen, M.E. van Molier, M. Berrevoets, C.A. Dooijes, D. Dubbink, H.J. Wijngaart, D.J. van de |
2008-09-24
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T cell re-targeting to EBV antigens following TCR gene transfer: CD28-containing receptors mediate enhanced antigen-specific IFNgamma production
(Article)
Schaft, N. Lankiewicz, B. Bolhuis, R.L.H. Willemsen, R.A. Debets, J.E.M.A. Drexhage, H.A. Berrevoets, C.A. Moss, D.J. Levitsky, V. Bonneville, M. Lee, S.P. McMichael, A.J. Gratama, J-W. |
2006-04-01
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Functional analysis of a novel androgen receptor mutation, Q902K, in an individual with partial androgen insensitivity.
(Article)
Umar, A. Berrevoets, C.A. Van, N.M. Leeuwen, M. van Verbiest, M. Kleijer, W.J. Dooijes, D. Grootegoed, J.A. Drop, S.L.S. Brinkmann, A.O. |
2005-01-01
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Distinct recognition modes of FXXLF and LXXLL motifs by the androgen receptor.
(Article)
Dubbink, H.J. Hersmus, R. Verma, C.S. Korput, H.A.G.M. van der Berrevoets, C.A. Tol, J. van Ziel-van der Made, C.J. Brinkmann, A.O. Pike, A.C. Trapman, J. |
2004-09-01
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Differential modulation of androgen receptor transcriptional activity by the nuclear receptor co-repressor (N-CoR).
(Article)
Berrevoets, C.A. Umar, A. Brinkmann, A.O. Trapman, J. |
2004-05-01
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Proteomic analysis of androgen-regulated protein expression in a mouse fetal vas deferens cell line
(Article)
Umar, A. Luider, T.M. Berrevoets, C.A. Grootegoed, J.A. Brinkmann, A.O. |
2003-04-01
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Proteomic analysis of androgen-regulated protein expression in a mouse fetal vas deferens cell line
(Article)
Umar, A. Luider, T.M. Berrevoets, C.A. Grootegoed, J.A. Brinkmann, A.O. |
2003-01-01
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