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psoriasis expression epidermal nb-uvb gata 3 expression psoriatic lesional keratinocyte treatment patient receptor gata 3 figure pathway cytokine therapy nb-uvb therapy dermatol differentiation lesional skin response epidermis flammation biopsy effect control il -23/il axis imq-induced skin nonlesional skin protein ifn-a result score t cells sample model balb /c mice nonlesional staining mouse irradiation poly-ic imq-induced study 17 pathway epidermal differentiation rig-i number lesion psoriatic skin netherland imiquimod level c 57bl mice analysis disease development factor lesional psoriatic skin transcription psoriasiform 17 pathways skin biopsies thickness dermatiti non-lesional hacat cells van der erasmus mc rotterdam 6 hours production rt-pcr application il -6 erythema reduction immunol imq-treated -23/il
4 Most Recent Publications
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Effective treatment of psoriasis with narrow-band UVB phototherapy is linked to suppression of the IFN and Th17 pathways
(Article)
Rácz, E. Prens, E.P. Staal, F.J.T. Fits, L. van der Kurek, D.M. Kant, M. Ridder, D. de Mourits, S. Baerveldt, E.M. Özgür, Z. IJcken, W.F.J. van Laman, J.D. |
2011-07-01
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GATA3 expression is decreased in psoriasis and during epidermal regeneration; induction by narrow-band UVB and IL-4
(Article)
Rácz, E. Kurek, D.M. Kant, M. Baerveldt, E.M. Florencia, E. Mourits, S. Ridder, D. de Laman, J.D. Fits, L. van der Prens, E.P. |
2011-05-23
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Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis
(Article)
Fits, L. van der Mourits, S. Lubberts, E.W. Voerman, J.S. Kant, M. Boon, L. Laman, J.D. Cornelissen, F.H.J. Mus, A.M. Florencia, E. Prens, E.P. |
2009-05-01
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IFN-α enhances poly-IC responses in human keratinocytes by inducing expression of cytosolic innate RNA receptors: Relevance for psoriasis
(Article)
Prens, E.P. Kant, M. Dijk, G. van Wel, L.I. van der Mourits, S. Fits, L. van der |
2008-04-01
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