Taghon, T.

tcrgd t-all analysis expression population mutation lineage t cells phf 6 sample notch phf 6 mutations op 9 cells differentiation op 9-dl cells tcrgd þ cells op 9-dl leukemia figure culture rearrangement 34highcd hematopoietic precursor t lineage cells adult number blood pathway generation lymphoblastic leukemia cd 34highcd cells cd thymocyte differentiation t-cell hesc-derived experiment result tcrab phenotype thymocyte system dp cells university representative receptor co-culture study van coppernolle tcra rearrangements lymphoblastic thymu deletion op 9-dl monolayers table presence marker stage sequencing 34ϩcd cd 34ϩ cells cd 34ϩcd cells ghent tcrgd þ populations mann – whitney protein nature frameshift t-all samples x chromosome op 9-gfp tcrab þ cells signi ficant differences stromal vandekerckhove structure von boehmer h hesc-derived t cells fl ow cytometry right protein blot analysis