Kraaipoel, R.J.

cholesterol 22 r-oh cholesterol pregnenolone 20 a-oh cholesterol cleavage side-chain reaction oxygen mitochondria conversion cytochrome cholesterol side-chain cleavage cytochrome p -450scc cortex mitochondria formation 22 cholesterol experiment result compound presence chapter cortex burstein -450scc 18 0 isocaproaldehyde side-chain cleavage incubation water nadph group -450 incorporation substrate addition hypothesis reduction intermediate side-chain cleavage reaction isocaproic acid system fragment medium method enzyme steroid concentration inhibition acetone powder mechanism r-di-oh phosphate amount chern molecule pathway stoichiometry type i isocaproic preparation scheme epoxyhydrase sample sterol study condition volume aminoglutethimide cytochrome p -450 18 0 2 acetone biophy oxygen atom effect oxygen consumption protein spectrum ~ 20 table 37° c