Díaz, J.A.

somatostatin tumor receptor patient analog somatostatin analogs octreotide study effect treatment journal somatostatin receptors growth neuroendocrine response combination cancer lanreotide trial survival metastatic therapy affinity disease carcinoid subtype phase antiproliferative binding activity dopamine efficacy gep-net molecule month oncology neuroendocrine tumors agent endocrinology octreotide lar sst 2 carcinoid tumors hormone pasireotide chimeric radiolabeled somatostatin receptor subtypes receptor subtypes suppl tumor growth tumor progression secretion randomized result progression peptide factor antiproliferative effect metastasi stratum european journal growth hormone stratum 1 tumours profile phase ii study release novel somatostatin analogs radiolabeled somatostatin analogs internalization promid study bim -23a mechanism midgut evidence control binding affinity novel progression-free survival growth factor