Van Leeuwen, E.M.M.

blood mutation t cells t-cell erasmus mc figure number patient proliferation control b cells disease ficiency rag 1 immunode activity analysis recombination idiopathic figure 1 defect erasmu article lymphocyte granulomatous disease b-cell netherland research 2011. thymu lymphocytopenia van dongen jj figure 2 cd 4ϩ american society rag activity protein repertoire age-matched infection nonswitched b cells cd 4ϩ lymphocytopenia figure 1 b granulomatou study immunode ficiency virus j exp med rag mutations taco library kuijper recombination activity thymus hypoplasia rag mutations blood september hypomorphic thymic volume amsterdam receptor result report center rotterdam center j clin data analysis department rag mutations hypomorphic mutations syndrome information t-cell proliferation omenn design cd 45ra blood donors function thymic function memory hiv infection immunode ficiency