Thrasher, A.J.

vector therapy expression number analysis gene therapy insertion blood figure level study lentiviral b cells patient leukemia spleen il 2rg mice scid-x transduced integration t-cell transplantation sffv.corag sample γ cpr-co γc reconstitution order antibody group promoter rag 1 expression wild-type 1-/- region t cells spleen cells american society transgene hematopoietic table result development sequence cpr-co b-cell protein murine sffv.corag 1-treated mice fl ow cytometry genomic pretransplant conditioning rag 1à/à mice month ficiency function receptor conditioning notch virus correction trial scid-x 1 rag 1 ucoe.corag chromosome immunodeficiency mutation rearrangement response clone animal population transfer lmo 2 1-treated cancer therapy vol wild-type cells insertion sites flow cytometry analysis