Rosenling, T.

sample protein metabolite analysis variation study sclerosis proteomic peptide patient control csf samples biomarker concentration cerebrospinal model proteome 4 ° c cerebrospinal fluid level disease cerebrospinal fl uid number validation sample storage freeze /thaw cycles method research fluid eae model blood change animal difference effect validation freeze result tissue factor signi room temperature table netherland individual spectrometry system mscl patients water inter-individual variation cycle figure -80 ° c group encephalomyeliti mikkat temperature column neurol fication /thaw material peak areas csf sample signi ficantly abundance brain serum myelin grant sclerosis patients inter-individual collection porcine csf mouse porcine gender chromatography ficant eae models