Sandkuijl, L.A.

patient mutation marker population study allele diabetes chromosome analysis region x syndrome type 2 diabetes table disease genet linkage syndrome subject type 1 diabetes netherland individual family haplotype genetic diagnosis deficiency sample renin genotype polymorphism hypertrophy distance dutch plasma hypertrophic cardiomyopathy rotterdam frequency result control angiotensin parent level model association mapping parents /guardians hsd 17b gene parkinsonism number method genome locus plasma renin value screening cardiomyopathy score library erasmus mc carrier prevalence linkage disequilibrium hypertrophic enzyme group t /a ratios c allele /c polymorphism university recessive primer receptor wild-type transcript ratio early-onset parkinsonism /guardian transcript gradient evidence estimate genomic regions