Rutten, G.E.H.M.

diabetes patient complication treatment health control diabetes control intervention level guideline study model intervention mixes treatment satisfaction quality type 2 diabetes score table baseline effect satisfaction hrqol macrovascular complications health effects value dutch disease care patients microvascular euroqol analysis lifetime macrovascular insulin state euroqol vas scores group diabetes care utility microvascular complications result diabetes treatment figure niessen p 2.gc patient characteristics netherland population obesity therapy insulin therapy implementation option estimate amputation life years p 1.gc guideline care cost-effectiveness blindness coefficient resource mortality problem hba 1c level instrument presence hba 1c levels 0.0001 characteristic effectiveness retinopathy incidence baseline scenario november lifetime costs anxiety /depression dimension fasting blood glucose eq 5d instrument