Weterings, E.

dna-pkc protein dna ends dna-pk substrate kinase autophosphorylation ligation activity dna-dependent protein kinase reaction repair presence dna substrate strand assay phosphorylation ligase dna-pkcs autophosphorylation dsb sites dna termini product terminus ku 80 ercc 1xpf addition binding accumulation laser carboxy processing molecule reaction mixtures termini interaction result ssdna complex ku 70/80 dna-dependent concentration level synapsi kinase activity region digestion recombination nuclease exonuclease mixture microirradiation 70/80 acids research replication single-stranded dsb repair recruitment subunit ku 70/80 heterodimer e.coli dna ligase xrs 6 cells nucleotide buffer artemi replication protein dsb site formation hairpin xrcc 4/ligase iv downloaded fragment ku 70/ku dna molecule place dnapkc polarity coli ssb protein intensity system wild-type