Kruining, J.

virus acyclic nucleoside phosphonates 2.2.15 hepatitis hepatocyte >100 compound duck hepatocytes hepatitis b virus ic 50 dhbv-infected duck hepatocytes concentration nucleoside activity effect infection acyclic phosphonate agents chemother clercq agent dhbv-infected culture chemother dhbv dna day 3 inhibitor culture medium hiv inhibitors incorporation medium hepatoma czech republic study antimicrob rotterdam table hbv infections replication antiretroviru production candidate test compounds hbv dna sequences heutink 1985. detection 2- phosphonylmethoxypropyl derivatives hepatoma cell lines department dna hbv production balzarini schalm 3 department 1993. erasmus university rotterdam 1.2 anti-dna virus activity vivo antiretrovirus activities dhbv dna-positive ducklings cell culture supernatants cytotoxic dot blot analysis cell culture assay 0.06 0.01 bethesda research laboratories plasmid pbr 322 28 february 1994/ wilde 31 10 4365145. 1991. references 1. balzarini hepatoma cell line tissue culture r autoradio 2180 vol extracellular hbv dna proliferation hybridization katholieke universiteit leuven prime-a-gene labelling system dot spot hybridization 3.2- kb genome