http://repub.eur.nl/res/aut/3722/ List of Publications en http://repub.eur.nl/static-eur/img/logo.png http://repub.eur.nl http://repub.eur.nl/res/pub/4115/ 1984-01-01T00:00:00Z In this paper we report the sequelae of a patient with an anomalous right coronary artery (RCA) originating from the pulmonary artery (PA) in association with a normal heart, operated upon at the age of 13 years. Three years after the end-to-side reimplantation of the RCA, with a rim of the PA, into the aorta, the surgical result has been evaluated by cineangiography. Before operation both coronary arteries were tortuous and increased in size. Afterwards the left coronary artery showed a normalized calibre, although the RCA remained tortuous with no decrease of the internal diameter. The notable postoperative changes in shape and size of the LCA may be due to the disappearance of the steal phenomenon. The lack of involutive changes in the RCA could be explained by its thinner wall. Left ventricular wall motion, evaluated under resting conditions and during an atrial pacing stress test, was found to be normal. http://repub.eur.nl/res/pub/4116/ 1984-01-01T00:00:00Z This is the fourth reported case of congenital arteriovenous fistula between the internal mammary artery and pulmonary artery. Precise and complete diagnostic evaluation is required to localize, delineate and appreciate the haemodynamic significance of this type of arteriovenous shunt. A brief review of the literature is given with suggestions for diagnosis. http://repub.eur.nl/res/pub/25781/ 1979-06-27T00:00:00Z The road from fertilized egg to newborn baby is a fascinating and complicated one. What happens to eggs that actually come in contact with spenns has been stuclied by many authors and has been summarized by Witschi in 1969. About 16% of the eggs do not cleave, either because they are not penetrated by sperms or because the mitotic mechanism does not function. Another 15% are lost during the first week, at various preimplantation stages ( cleavage and blastocyst stages ). The stage of early implantation and development during the second week brings a further lossof 27%. In the third to sixth week there is a loss of 8% and the late abortion loss is about 3%. Live births will then amount to only 31%. It has been shown that 1-12% of all these newborn children carry some major congenital malformation recognizable at or shortly after birth ( Yerushalmy, 1969; Lilienfeld, 1969 ), Reports of congenital malformations show congenital heart malformations in about 0.8% of total births ( Kerrebijn, 1964; Hoffman and Christianson, 1978 ). In the Netherlands with 177.090 newborns in 1976 this will be about 1400 per year of which 123 were surgically corrected and 416 died in the first year of life ( Centraal Bureau voor Statistiek, 1976, 1978 ). The majority of congenital he'art malfonnations are of rmknown etiology and are believed to be the result of the interaction of environmental and genetic influences ( Nora, 1968 ). The risk for recurrence of the same lesion in cases with an affected parent or sibling is small but exceeds the expectation risk for the same lesion in the general population. Vertical transmission of atrial septal defects through four generations has been described (Lynch et al., 1978 ) . These children bom with congenital heart malfonnations are of special interest to the paediatric cardiologist and cardiovascular surgeon. http://repub.eur.nl/res/pub/25782/ 1979-06-27T00:00:00Z The road from fertilized egg to newborn baby is a fascinating and complicated one. What happens to eggs that actually come in contact with spenns has been stuclied by many authors and has been summarized by Witschi in 1969. About 16% of the eggs do not cleave, either because they are not penetrated by sperms or because the mitotic mechanism does not function. Another 15% are lost during the first week, at various preimplantation stages ( cleavage and blastocyst stages ). The stage of early implantation and development during the second week brings a further lossof 27%. In the third to sixth week there is a loss of 8% and the late abortion loss is about 3%. Live births will then amount to only 31%. It has been shown that 1-12% of all these newborn children carry some major congenital malformation recognizable at or shortly after birth ( Yerushalmy, 1969; Lilienfeld, 1969 ), Reports of congenital malformations show congenital heart malformations in about 0.8% of total births ( Kerrebijn, 1964; Hoffman and Christianson, 1978 ). In the Netherlands with 177.090 newborns in 1976 this will be about 1400 per year of which 123 were surgically corrected and 416 died in the first year of life ( Centraal Bureau voor Statistiek, 1976, 1978 ). The majority of congenital he'art malfonnations are of rmknown etiology and are believed to be the result of the interaction of environmental and genetic influences ( Nora, 1968 ). The risk for recurrence of the same lesion in cases with an affected parent or sibling is small but exceeds the expectation risk for the same lesion in the general population. Vertical transmission of atrial septal defects through four generations has been described (Lynch et al., 1978 ) . These children bom with congenital heart malfonnations are of special interest to the paediatric cardiologist and cardiovascular surgeon.